Cytokeratin 1 anticorps
Aperçu rapide pour Cytokeratin 1 anticorps (ABIN7673427)
Antigène
Voir toutes Cytokeratin 1 (KRT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- KRT1-specific antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: Peptide
Immunogen: keratin 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Date de péremption
- 12 months
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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Autre désignation
- KRT1
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Sujet
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Synonyms: Keratin, type II cytoskeletal 1|67 kDa cytokeratin|Cytokeratin-1 (CK-1)|Hair alpha protein|Keratin-1 (K1)|Type-II keratin Kb1|KRT1|KRTA
Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.
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Poids moléculaire
- 67 kDa
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UniProt
- P04264
Antigène
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